Acne is a disorder that is difficult for most young people, because of the small lumps on the face of it it will damage their appearance. But be careful if you use antibiotic drugs to cope with severe acne, because it can cause disease much more dangerous.
Sometimes severe acne that does not work with regular medications. Some cases of acne sometimes get treatment with antibiotics. But the provision of hard drugs should not be carelessly be with permission doctor.
Not all cases of acne require treatment with antibiotics, because antibiotics are generally given if the patient has severe acne levels, in this case severity assessed by the examining physician.
Generally acne is quite severe, including nodular and cystic acne. In such cases dermatologists will prescribe antibiotics, especially if the stains that appear to be at risk of serious infection. But if the acne is only on the surface of the antibiotics are not needed.
Now prove that antibiotics are widely prescribed to help control the emergence of severe acne, in a small number of patients, causing inflammatory bowel disease.
Intestinal disorders associated with the treatment of acne is the result of a rare, says Dr. David Margolis, a dermatologist and lead author of the study in the American Journal of Gastroenterology.
However, previous studies mentioned that the acne drug isotretinoin, commonly known under the brand name Accutane, may be the cause of inflammatory bowel disease in a small number of patients who underwent treatment for severe acne.
Seeing the many people who get treatment isotretinoin has been taking antibiotics for months or possibly years, Margolis and his colleagues at the University of Pennsylvania wanted to observe whether antibiotics could play a role in triggering intestinal disease.
Carrying up to 90% of adolescents and young people with acne try to overcome this disorder at some point. Drugs of the tetracycline family is the most commonly prescribed antibiotics to treat severe acne.
"These drugs limit the occurrence and outbreak of acne scarring. The drug is very effective and has been used for many years," said Margolis.
In his study, the researchers looked at medical records of more than 94,000 adolescents and young adults in the UK are diagnosed with acne between 1998 and 2006.
Antibiotics are given to work with some mechanism, but the most important thing is to reduce the number of bacteria in and around the follicles, as reported from Dermatology.about.com, Saturday (4/23/2011) ago.
The function of other antibiotics is to reduce the chemical irritation produced by white blood cells, reducing the concentration of free fatty acids in the sebum and reduce the inflammatory response (inflammation).
There are several antibiotics that are usually given to cope with acne are:
Tetracycline
This most widely prescribed antibiotics for acne, dose is given more and more reduced in line with a visible reduction in acne lesions. But antibiotics should not be given to pregnant women or children under the age of 9 years.
Erythromycin
This antibiotic has anti-inflammatory properties that help reduce redness in lesions (sores), acne and kill bacteria. Dosages vary depending on the type used. But antibiotics can cause abdominal pain and nausea.
Minocycline
This antibiotic is a derivative of tetracycline that effectively been used as an acne treatment. The initial dose given is usually 50-100 mg per day. But the side effects that emerge usually change the color of skin and teeth if consumed for long periods.
The researchers found that long-term use of antibiotics seems to trigger the risk of inflammatory bowel disease has doubled. Of the 207 cases of inflammatory bowel disease are diagnosed in 94,487 patients in the study, 152 (0.26% of all study participants) who uses one of three tetracycline-based antibiotics and 55 (0.14%) not taking the drug.
Patients taking one of three drugs, doxycycline, seem to have a slightly higher risk (0.21%) to develop inflammatory bowel disease compared with patients taking minocycline (risk 0.17%) or tetracyclines (risk 0.20%) .
"Relations are perhaps the most prominent Crohn's disease," said Margolis.
Crohn's disease is an inflammation of the lining of the digestive tract, which can cause abdominal pain, severe diarrhea and malnutrition. This disease affects about 400,000 people in the U.S.. Approximately 600,000 Americans suffer from other inflammatory bowel diseases, namely ulcerative colitis. Both diseases are treated with anti-inflammatory drugs and some cases of surgical complications can be done.
Potential risks should be a consideration for those who obtain prescription drugs tetracycline-based antibiotics, and this finding could be the foundation for further research to determine the relationship between acne medication with intestinal disorders.
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