New Breast Cancer Genes Found

British researchers found three major gene causes breast cancer the most common. The findings are expected to facilitate the manufacture of treatment and new drugs are more effective. Currently, breast cancer remains a scourge for women.

Of course these findings are very exciting, although still in early stages of research. That way, the new drugs will be available within five years. During the five-year study, researchers funded by the UK National Health Service (NHS) and funding from the charity Breakthrough Breast Cancer study the DNA of 104 patients with breast cancer, including the many British citizens. All women who become participants have something known as estrogen receptor positive breast cancer.

This gene which contributes four of five patients with breast tumors and the cause of most of the 12,000 lives lost in a year. Called positive for estrogen to be "food" and fuel for the tumor by attaching to proteins on the surface of cancer cells known as receptors. Many treatments are now frequently used, including the use of drugs tamoxifen for breast cancer patients the most widely used, which works by cutting the supply of this estrogen.

However, tumors often become resistant to treatment so that the cause behind the cancer returning after surgery, or spread throughout the body with potentially fatal consequences. The key role of sex hormones in the process means that the genetics of these estrogen receptors have been studied intensively for decades. So, researchers from the Breakthrough Breast Cancer Research Centre at the Institute of Cancer Research, London, England, interested to find the nearest of DNA that protect the three genes that had been previously unknown.

Dr Anita Dunbier, the study's lead author, said it discovered a new gene. This is like finding gold in Trafalgar Square, London, England. "It is too obvious to be true. We have to examine it very thoroughly to make sure (that it) is not only a false discovery," he said as quoted Dailymail. "We now have see further how this gene works, but this discovery could lead to new therapeutic methods are likely to benefit women with breast cancer in the near future, "she added.

The most important thing, even though the gene is located close to the estrogen receptor, they work separately. If the dispensing of new drugs from scratch, it can last for years. However, the research team hopes to accelerate the process of testing drugs that already exist in the market for the treatment of other diseases. However, follow-up about this, written detailed in the journal PLoS Genetics, is still in its infancy and needs much more research.

"This research is interesting because it shows that while the estrogen receptor is the major cause of hormonal breast cancer, there is another door that appears to influence breast cancer progression," said one researcher Professor Mitch Dowsett.